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Jordi Folch-Pi Memorial Award for 1989

Dr Wendy B. Macklin

Dr Wendy B. Macklin

    Dr. Wendy Macklin was the 1989 recipient of the Jordi-Folch-Pi Memorial Award for her work to elucidate the properties and function of the myelin proteolipid protein. Dr. Macklin received her B.S. degree from Stanford University, M.S. degree from Yale University School of Medicine, and Ph.D from Stanford University in 1979. She was a postdoctoral fellow with Dr. Marjorie Lees at the E.K. Shriver Center for Mental Retardation and Massachusetts General Hospital for three years. Her first faculty position was in the Department of Biochemistry and Molecular Biology at Louisiana State University School of Medicine, starting in 1982. She moved to the Mental Retardation Center in the Neuropsychiatric Institute at UCLA in 1985, where she was promoted to Associate Professor and then to Professor in 1993. She moved to the Department of Neurosciences at the Cleveland Clinic Foundation in 1995, and joined the faculty at Case Western University School of Medicine in 2000. Her research has focused on control of oligodendrocyte differentiation, with a particular emphasis on the myelin proteolipid protein. She has characterized the control of the expression of the proteolipid protein gene in normal and mutant mice, studying promoter activity, RNA stability and protein processing. She has used the proteolipid protein promoter to generate a number of transgenic mice, overexpressing proteins specifically in cells in the oligodendrocyte lineage.     Dr. Macklin has been an active member of the American Society of Neurochemistry. She has been on the Program Committee five times; she served on the Publications Committee from 1983-1985, the Jordi Folch-Pi Memorial Award Selection Committee from 1991-1995, and the Marian Kies Memorial Award Selection Committee from 1992-1995; she was chair of the local organizing committee for the 1995 annual meeting of the Society; and she has been a member of the Council of the Society twice, from 1993-1997 and currently (1999-2003). She served as President of the ASN from 2005-2007.    Dr. Macklin has served on many study sections, including several at the NIH, one at the NSF, and two at the National Multiple Sclerosis Society. She is on the editorial boards of several journals, including the Journal of Neuroscience, Journal of Neurochemistry, the Journal of Neuroscience Research, Developmental Neuroscience, and the International Journal of Developmental Neuroscience.