Poster and Oral Session Presentations

The full scientific program (Symposium, Colloquium, and Workshops) can be found at: http://www.asneurochem.org/SciProgrms/ASN2005SciProg.htm

Posters are divided into two sessions, each lasting for 2 consecutive days (Sunday-Monday or Tuesday-Wednesday). Posters will be available for viewing each day beginning at 7 am until the end of that day’s sessions. Approximately 2 hours each day (beginning immediately after lunch) will be exclusively dedicated for poster viewing. Authors are expected to be present at their posters from 1:30 to 2:30 each day.

Poster instructions

The four oral sessions are each scheduled for 1hr 45 minutes. These sessions will begin at approximately 5:00 pm on the indicated days. Please refer to the Program booklet for exact times and places.

Posters - Sunday and Monday

Posters- Tuesday and Wednesday

Oral Sessions


Poster Sessions PSM01 to PSM08 (Sunday - Monday)

Poster Session PSM01 Neurogenesis and Regeneration

PSM1-01 Waschek, J.A., Armstrong, B.D., Abad, C., Chhith, S., Rodriguez, W.I., Cheung-Lau, G., Ngo, D.
Critical involvement of CD4+ T-lymphocytes in axotomy-induced PACAP gene expression in mouse facial motor neurons

PSM1-02 Smith, M.C., Chang, A., Staugaitis, S.M., Trapp, B.D.
Neurogenesis in the Lesions of Multiple Sclerosis

PSM1-03 Warrington, A.E., Bieber, A.J., Van Keulen, V. , Ciric, B. , Pease, L.R. , Rodriguez, M.
A recombinant human IgM promotes remyelination at doses analogous to a growth factor

PSM1-04 Baek, R.C. , Lee, J.P. , Seyfried, T.N. , Snyder, E.Y.
Neural Stem Cell Transplantation Reduces Brain GM2 and GA2 Content in a Mouse Model of Sandhoff Disease

PSM1-05 Svetlov, S.I. , Kukekov, V.G. , Wang, K.K. , Hayes, R.L.
LPA, endocannabinoids, and their receptors in the development of neural progenitors

PSM1-06 Seehus, C.R., Schneider, B.L., Capowski, E.E., Svendsen, C.N.
Controlling Transgene Expression by Lentiviral Infection of Human Neural Progenitor Cells

PSM1-07 Alagappan, D. , Felling, R.J. , Levison, S.W.
Perinatal Hypoxia/Ischemia Enhances EGF Responsiveness of SVZ Neural Stem/Progenitors

PSM1-08 Nelson, A.D. , Svendsen, C.N.
FGF-2 is Sufficient but Not Completely Necessary for Neurogenesis from hNPCs

PSM1-09 Yu, R.K., Dinkins, M.B., Su, C.Y., Liour, S.S.
Spatiotemporal expression of GM1 in Murine Medial Pallial Neural Progenitor Cells

PSM1-10 Klein, S.M., Svendsen, C.N.
EAAT2 expression by neural progenitor cell derived astrocytes


Poster Session PSM-02 Alzheimer's and Aging

PSM2-01 CHAI, Y.F., HAUGHEY, N.J.
Amyloid- b Enhances Purinotoxicity by Caspase3 Mediated Cleavage of the P2X4 C-Terminal

PSM2-02 Chauhan, N.B., Sandoval, J.C.
Effect of Aged Garlic Extract on Morris Water maze Performance in Tg2576

PSM2-03 Martin, M. , Readhead, C.
In Vivo Beta-Amyloid Plaques Visualized through MRI in Mouse Model of Alzheimer's Disease

PSM2-04 Chen, C. , Duce, J.A. , Hollander, W. , Kipling, D. , Rosene, D.L. , Abraham, C.R.
Gene expression profiles in aging rhesus monkey brain

PSM2-05 Sirkis, D.W. , Kraft, A.D. , Stein, T.D. , Johnson, D.A. , Johnson, J.A.
Activation of the antioxidant response element in the prefrontal cortex of Tg2576 mice expressing mutant amyloid precursor protein

PSM2-06 Chen, C., Oh, S., Abraham, C.R.
Visualization of Homodimeric and Heterodimeric Interactions between APP and Notch2 Proteins in Living Cells Using BiFC analysis

PSM2-07 Ferrari, D.C., Bourne, K.Z., Perez-Polo, J.R.
Roles of the different beta-Amyloid molecular species in cellular binding and pathology in AlzheimerÕs disease

PSM2-08 Polak, P.E. , Kalinin, S. , Madrigal, J.M. , Gavrilyuk, V. , Marien, M. , Feinstein, D.L.
Beta-Amyloid Dependent Expression of Inducible Nitric Oxide Synthase in Neurons: Prevention by a2-Adrenergic Receptor Antagonist

PSM2-09 Gibson, G.E., Huang, H.M., Chen, H.L.
Select oxidants produce changes in endoplasmic reticulum Ca2+ stores reminiscent of those in patients with Alzheimer

PSM2-10 Kalinin, S.A. , Chauhan, N. , Gavrilyuk, V.G. , Galea, E. , Feinstein, D.L.
Possible Mechanisms of Noradrenergic Action in TgAPP Mice

PSM2-11 Quintanilla, R.A., Godoy, J.A., Toro, A., Santos, M.J., Inestrosa, N.C.
Peroxisomal Proliferation Prevents b-Amyloid-Neurotoxicity in Rat Hippocampal Neurons

PSM2-12 Brittain, G., Bethea, J.R.
The Role of the Alternative NF-kB Signaling Pathway in the Induction of AD Pathogenesis

PSM2-13 Seabrook, T.J., Jiang, L., Maier, M., Lemere, C.A.
Effects of minocycline on Alzheimer's disease pathogenesis.

PSM2-14 Lee, H.G., Ueda, M., Zhu, X., Perry, G., Smith, M.A.
Ectopic Localization of Active Smad2 in the Vulnerable Neurons in Alzheimer Disease

PSM2-15 Combs, C.K., Floden, A.M.
Beta-Amyloid Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor and NMDA Receptors

PSM2-16 Kandimalla, K.K., Curran, G.L., Holasek, S.S., Gilles, E.J., Wengenack, T.M., Poduslo, J.F.
Pharmacokinetic Analysis of BBB Transport of 125I-AB40 in WT/AD Transgenic Mice and Its Implication for Amyloid Plaque Formation

PSM2-17 Wu, C.Y. , Wei, J.J. , Polak, P.E. , Sharp, A.R. , Mao, J.L. , Feinstein, D.L. , Gould, R.M. , Nichols, L. , Park, K., Cai, L. , Innis, R.B.
Development of Novel Amyloid Imaging Agents Based Upon Thioflavins

PSM2-18 Giles, K.E., Kandimalla, K.K., Ramirez-Alvarado, M., Poduslo, J.F.
Development of AB40 Derivatives That Do Not Form Fibrils As MRI Contrast Agents For Detecting Alzheimer's Disease Amyloid Plaques


Poster Session PSM-03 Death and Survival

PSM3-01 Das, A., Karmakar, S., Saha, A., Banik, N.L., Ray, S.K.
Dexamethasone decreases while acetazolomide increases temozolomide induced apoptosis in human glioblastoma U87MG cells

PSM3-02 Karmakar, S., Saha, A., Das, A., Banik, N.L., Ray, S.K.
Curcumin activated mutiple molecular mechamisms for apoptosis in human glioblastoma T98G cells

PSM3-03 Fiscus, R.R., Tsim, J., Wong, C.Y., Leung, L.H.
Phosphodiesterase inhibitors protect against apoptotic cell death induced by nitric oxide or rotenone in NG108-15 cells

PSM3-04 Banik, N.L., Sribnick, E.A., Ray, S.K.
Estrogen attenuates glutamate-induced death in a spinal motoneuron cell line

PSM3-05 Franklin, J.L., Kirkland, R.A.
BAX AND REACTIVE OXYGEN IN CYTOCHROME c-DEPLETED NEURONS

PSM3-06 Ray, S.K., Sribnick, E.A., Matzelle, D.D., Banik, N.L.
Combination of TUNEL and double immunofluorescent labeling demonstrated calpain in neuronal apoptosis in rat spinal cord injury

PSM3-07 Spagnolo, A. , Lichtor, T. , Glick, R. , Dello Russo, C. , Murphy, P. , Lin, H. , Gavrilyuk, V. , Feinstein, D.L.
Thiazolidinediones Induce Glioma Toxicity: Involvement of Mitochondria and ROS

PSM3-08 Podratz, J.L., Knight, A.M., Windebank, A.J.
cisplatin-induced delayed cell death in drg neurons is associated with altered mitochondrial function.

PSM3-09 Bieberich, E.,
Slips versus rafts: A novel mechanism regulating cell fate decisions by sphingolipid-induced remodeling of cell signaling platform

PSM3-10 Wang, G. , Silva, J. , Krishnamurthy, K. , Condie, B.G. , Bieberich, E.
Ceramide induces apoptosis selectively in pluripotent stem cells and promotes neuronal differentiation of neuroprogenitors

PSM3-11 Wolf, G., Schroeter, A., Andrabi, S., Horn, T.
Modulation of NMDA-induced calcium transients by NO applications simultaneous or prior to the stimulus: cell death or survival

PSM3-12 Herrero, R., Yi, J.H., Hazell, A.S.
Focussed microarray analysis reveals induction of TRAIL in cerebral cortex following fluid-percussion injury in the rat

PSM3-13 Saqr, H.E., Omran, O.M., Oblinger, J.L., Yates, A.J.
GD3 Induces Apoptosis in U-1242 MG Glioma Cells Through a Caspase-8 Dependent PathwaY..

PSM3-14 Zimmermann, A.K. , Loucks, F.A. , Bouchard, R.J. , Heidenreich, K.A. , Linseman, D.A.
Inhibitors of Bcl-2/x(L) function elicit glutathione-sensitive neuronal death and oxidation of the mitochondrial ANT

PSM3-15 Monfort, P., Felipo, V.
SEQUENTIAL ACTIVATION OF GUANYLATE CYCLASE, PKG AND cGMP-DEGRADING PHOSPHODIESTERASE IN LTP. ALTERATIONS IN HYPERAMMONEMIA

PSM3-16 Bazan, N., Marcheselli, V.L. 1, Mukherjee, P.K.1, Hu, J.2, Bok, D.2, Hardy, M.1
Neurotrophic growth factors up-regulate neuroprotectin D1 (NPD1) synthesis and anti-apoptotic signaling in human retinal pigment epithelial (RPE) cells.


Poster Session PSM-04 Gene Expression and Signalling I

PSM4-01 LeBlanc, S.E. , Srinivasan, R. , Ferri, C. , Mager, G.M. , Gillian-Daniel, A.L. , Wrabetz, L. , Svaren, J.
Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox-20 during peripheral nerve myelination

PSM4-02 Mager, G.M., Srinivasan, R., Ward, R.M., Mayer, J., Svaren, J.P.
Nab2 represses Transcription by recruiting the Nucleosome Remodeling and Histone Deacetylase Complex

PSM4-03 Jakel, R.J. , Kern, J.T. , Johnson, D.A. , Johnson, J.A.
6-Hydroxydopamine activates the antioxidant response element through oxidative, excitotoxic, and structural factors

PSM4-04 Royland, J.E., Geller, A.M.
Gene Expression in a Retinal Model of Age-Related Susceptibility

PSM4-05 Kodavanti, P.R., Royland, J.E.
Gene expression profiles in the developing rat cerebellum and hippocampus

PSM4-06 Molloy, G.R., Willis, D., Zhang, Y.
Transcription of brain creatine kinase in U87-MG glioblastoma is modulated by factor AP2

PSM4-07 Greuel, B.T. , Pereira, B. , Sample, M. , Wight, P.A.
Regulation of myelin proteolipid protein gene expression: Molecular dissection of the antisilencer/enhancer region in intron 1.

PSM4-08 Chavez-Gutizrrez, L. , Matta, E. , Osuna, J. , Joseph-Bravo, P. , Maigret, B. , Charli, J.L.
Homology modelling and site directed mutagenesis of pyroglutamyl peptidase II. Omega- versus amino-peptidase specificy.

PSM4-09 Dobretsova, A. , Lichti, C.F. , Wight, P.A.
Characterization of the enhanceosome formed on the myelin proteolipid gene by DNA affinity chromatography and mass spectrometry

PSM4-10 Cheema, T.A., Ward, C., Fisher, S.K.
Thrombin enhances osmosensitive release of taurine from human 1321N1 astrocytomas: role of Volume Sensitive Organic Anion Channel


Poster Session PSM-05 Glia and Inflammation I

PSM5-01 Brenner, M. , Li, R. , Su, M. , Johnson, A.B. , van der Knaap, M.S. , Salomons, G.S. , Goldman, J., Quinlan, R. Messing, A.
GFAP mutations account for all forms of Alexander disease

PSM5-02 Hensley, K., Mhatre, M., Mou, S., Pye, N., Szweda, L.
Regulated Glutathionylation in Astrocytes : A New Aspect of Neuroinflammation

PSM5-03 Messing, A., Connor, J.X., Hagemann, T.L.
Generation and characterization of mice carrying Alexander disease-associated mutations in GFAP

PSM5-04 Zou, S.P., Adams, M.H., Zhao, T.Y., El-Hage, N., Hauser, K.F., Bruce-Keller, A.J., Knapp, P.E.
Transcription Factor Activity In Astrocytes: Interactions Between HIV-1 Tat And Opiates

PSM5-05 Silva, W.I. , Vel‡zquez, G. , Rubio-D‡vila, M. , Miranda, J.D. , Maldonado, H.M. , Jard-n, J. , Aquino, E. , Mayol, N. , Cruz, A.
Caveolin Isoform Expression during Differentiation of C6 Glioma Cells

PSM5-06 Jayakumar, A.R., Panickar, K.S., Norenberg, M.D.
Intracellular Signaling Pathways in Ammonia-induced Astrocyte Dysfunction

PSM5-07 Kintner, D.B. , Look, A. , Shull, G.E. , Sun, D.D.
Activation of ERK1/2 Stimulates NHE1 Activity in Astrocytes in Response to in vitro Ischemia

PSM5-08 Rama Rao, K.V., Norenberg, M.D.
Role of aquaporin-4 in the mechanism of ammonia-induced astrocyte swelling

PSM5-09 Domowicz, M.S., Mueller, M.M., Henry, J.G., Schwartz, N.B.
Role of aggrecan in astrocyte differentiation

PSM5-10 Mirochnic, S., Evrard, S.G., Duhalde Vega, M., Tagliaferro, P., Caltana, L., Brusco, A.
Neuronal and astroglial response to a long abstinence period after a low, chronic ethanol exposure in the adolescent rat.

PSM5-11 Connor, J.R., Zhang, X.
Microglial iron status influences survival of oligodendrocytes


Poster Session PSM-06 Metabolism

PSM6-01 Sickmann, H.M. , Schousboe, A. , Fosgerau, K. , Waagepetersen, H.S.
Lactate originating from glycogen is compartmentalized from glucose derived lactate in cultured astrocytes.

PSM6-02 Zielke, H.R. , Zielke, C.L. , Baab, P.J. , Tsukamoto, T. , Ferraris, D. , Rojas, C. , Wozniak, K. , Slusher, B.
inhibition of glutamine hydrolysis in the interstitial fluid of the rat brain by a glutaminase inhibitor, gpi-20767

PSM6-03 Cole, J.T. , Sweatt, A.J. , Wallin, R. , LaNoue, K.F. , Lynch, C.J. , Hutson, S.M.
Branched-Chain α Keto-Acid Dehydrogenase is a neuronal enzyme in brain.

PSM6-04 Schroeder, M.L. , Sneve, M. , Drewes, L.R.
Expression of Monocarboxylic Acid Transporter mRNA in the Developing Rat Brain Cortex

PSM6-06 Golovko, M.Y. , Faergeman, N.J. , Cole, N.B. , Castagnet, P.I. , Nussbaum, R.L. , Murphy, E.J.
alpha-Synuclein Gene-Ablation Decreases Brain Palmitate Uptake and Alters Palmitate Metabolism in Brain Phospholipids

PSM6-07 Akar, C.A. , Colca, J. , Dello Russo, C. , Spagnolo, A. , Gavrilyuk, V. , Feinstein, D.L.
Receptor independent effects of thiazolidinediones in astrocytes

PSM6-08 Krasnikov, B.F. , Ratan, R.R. , Gibson, G.E. , Iismaa, S. , Cooper , A.J.
Transglutaminase Activity in Non-Synaptosomal Mouse Brain and Liver Mitochondria

PSM6-09 Brichac, J., Honzatko, A., Picklo, M.J.
Different enantioselectivity of 4-hydroxy-trans-2-nonenal oxidation in rat brain and liver mitochondria

PSM6-10 Honzatko, A., Brichac, J., Murphy, T.C., Mosley, D.M., Picklo, M.J.
Stereoselective detoxification of trans-4-hydroxy-2-nonenal by rat brain mitochondria.

PSM6-11 Spanier, J.A., Drewes, L.R.
protein-protein interaction technologies for identifying mct1 regulatory proteins

PSM6-12 Khairova, R.A., Lieberman, E.M.
NAAG, glutamate and NO - induced block of action potential generation and propagation in the crayfish nerve fiber.

PSM6-13 Hewett, S.J. , Silakova, J.S. , Bonventre, J.V. , Hewett, J.A.
Reduced Excitotoxic Neuronal Degeneration in Mice Deficient in Cytosolic Phospholipase A2

PSM6-14 Denny, C.A., Chalifoux, J.R., Kim, Y.P., Seyfried, T.N.
Retinal Glycosphingolipid Abnormalities in Sandhoff and GM1 Gangliosidosis mice

PSM6-15 Denny, C.A. , Kasperzyk, J.L. , Gorham, K.N. , Bronson, R.T. , Seyfried, T.N.
Caloric Restriction Extends Longevity without Altering Brain Lipid Composition or Cytoplasmic Neuronal Vacuoles in Sandhoff mice

PSM6-16 Gerstner, J.R., Vander Heyden, W.M., Landry, C.F.
Diurnal regulation of brain fatty acid binding protein (fabp7) mRNA and poly(A) tail length in the rodent brain.


Poster Session PSM-07 Spinal Cord

PSM7-01 Miranpuri, G.S. , Vemuganti, R. , DomBourian, M.G. , Turner, N.A. , Gerovac, T.A. , Tureyen, K. , Isaacson, J.W. , Miletic, V. , Resnick, D.K.
Differential expression of nociceptive genes influence pain behavior following spinal cord injury in adult rats

PSM7-02 Kigerl, K.A. , Rivest, S. , Popovich, P.G.
Regulation of innate immunity after spinal cord injury in mice: involvement of toll-like (TLR) receptors

PSM7-03 Lucin, K.M., Sanders, V.M., Jones, T.B., Malarkey, W.B., Popovich, P.G.
Alterations in sympathetic nervous system and hypothalamic-pituitary-adrenal axis function after experimental spinal cord injury

PSM7-04 Golder, F.J., Mitchell, G.S.
Spinal synaptic plasticity following intermittent hypoxia improves respiratory function after chronic cervical spinal cord injury

PSM7-05 Knight, A.M. , Georgi, S. , Issa, A. , De Ruiter, M. , Yaszemski, M.J. , Windebank, A.J.
Peptide attachment to biodegradable polymers for axonal guidance in spinal cord injury

PSM7-06 Banik, N.L., Sribnick, E.A., Matzelle, D.D., Wilford, G.G., Ray, S.K.
Estrogen attenuates neurodegeneration and improves motor function in the chronic model of spinal cord injury

PSM7-07 Karkora, A.C., ,M.Amin,E.Enany,R.Elbakary andS.Elgendy
clinical anatomical studies on the spinal cord of the egyptian goat

PSM7-08 Chen, Q., Zhou, L., Shine, H.D.
Acute injury is required for Neurotrophin-3 induced axonal plasticity in the spinal cord

PSM7-09 Skoff, Adler,
INFLAMMATORY CYTOKINES REGULATE NOCICEPTIVE PEPTIDES THROUGH NERVE GROWTH FACTOR


Poster Session PSM-08 Oligodendrocyte Biology

PSM8-01 Knapp, P.E., Zou, S.P., Alimova, Y.V., Hauser, K.F., Adjan, V.V.
Specific deficiency of kappa-opioid receptors in oligodendrocytes in the CNS of jimpy mice

PSM8-02 Dennis, J., White, M.A., Fox, M.A., Afshari, F.S., Fuss, B.
Phosphodiesterase-Ialpha/AutotaxinÕs matricellular properties facilitate process formation in oligodendroglial cells

PSM8-03 Gardinier, M.V., Allamargot, C., Koch, M.S., Lee, Y., Menon, K.
Myelin/oligodendrocyte glycoprotein: Receptor endocytosis, membrane targeting, and an intracellular partner

PSM8-04 DeBruin, L., Haines, J., LaForest, A., Harauz, G.
Developmental partitioning of MBP into myelin microdomains

PSM8-05 Boggs, J.M., Arvanitis, D.N., Min, W., Gong , Y.
Two Types of Low Density Detergent-Insoluble Membrane Domains from Myelin

PSM8-06 Feltri, M.L. , Previtali, S.C. , Zambroni, D. , Dati, G. , Occhi, S. , Dina, G. , Del Carro, U. , Campbell, K. , Saito, F. , Quattrini, A. , Wrabetz, L.
alpha6beta4 integrin confers stability to peripheral myelin.

PSM8-07 Eichberg, J., Konde, V.B., Garga, V., Rea, M.A.
Trafficking of wild type and cytoplasmic domain-mutated myelin protein zero-GFP in living Schwann cells

PSM8-08 Taylor, C.M. , Karim, M. , Marta, C.B. , Han, D. , Rasband, M.N. , Pfeiffer, S.E.
the myelin proteome II: updated functional proteomic mapping of the myelin membrane

PSM8-09 Wang, Y. , Gould, R.M. , Stankoff, B. , Lubetzki, C. , Wu, C. , Polak, P.E. , Wei, J. , Mao, J. , Lankin, D.C. , Feinstein, D.L. , Zalc, B.
Development of Molecular Probes for In Vivo Studies of Myelin

PSM8-10 Gould, R.M. , Morrison, H.G. , Gilland, E. , Campbell, R.K.
Evolution of myelin proteins: homologs identified in the ascidian (Ciona intestinalis) genome

PSM8-11 Garcia, C.I., Paez, P.M., Soto, E.F., Pasquini, J.M.
cDNA array in two oligodendroglial cell lines overexpressing transferrin show enhanced neurosteroids and mitochondrial activity.

PSM8-12 Calatayud, C.A., Garc'a , C.I., Paez , P.M., Soto, E.F., Pasquini , J.M., Pasquini, L.A.
A decrease in proteasome activity induces an activation of the myelin basic protein promoter.

PSM8-13 De Vries, G.H. , Thomas, S.
Angiogenic Expression Profile of Neurofibromin-Deficient Schwann Cells and Regulation by Neurofibromin GAP Related Domain

PSM8-14 Amici, S.A., Notterpek, L.
Peripheral myelin protein 22 forms a complex with beta4 integrin in the Schwann cell membrane

PSM8-15 Boggs, J.M., Gao, W., Wang, M., Hirahara, Y., Gong, Y., Arvanitis, D.N., Min, W.
A Glycosynapse in Myelin?

PSM8-16 Anitei, M. , Ifrim, M.F. , Ewart, M.A. , Bansal, R. , Carson , J.H. , Pfeiffer, S.E.
The Exocyst Regulates Myelin Formation and Maintenance.

PSM8-17 Nogaroli, L., Payne, S.G. , Spiegel, S. , Fuss, B.
Regulation of Oligodendrocyte Process Formation via PD-Ialpha/ATX and LPA.

PSM8-18 Zand, R. , Pointer-Keenan, C.D. , Lee, D.K. , Hallok, K. , Tan, A. , Ramamoorthy, A.
Abstract title A Solid State NMR Study of MBP Interaction With Lipid Bilayers

PSM8-19 Wang, J. , Wu, G. , Lu, Z. , Leone, P. , Ledeen, R.W.
Myelin lipid deficiency in aspartoacylase-null (tremor) rats, model for Canavan disease: specific deficit of cerebrosides


Poster Sessions PTW01 to PTW08 (Tuesday - Wednesday)

Poster Session PTW-01 Receptors, transmitters, and channels

PTW1-01 Anastasio, N.C., Johnson, K.M.
Pharmacological Analysis of Phencyclidine-Induced Regulation of the NMDA Receptor

PTW1-02 Mehta, M., Zaghloul, A., Wieraszko, A., Banerjee, P.
5-HT1A receptor signaling in neonatal mousebrain.

PTW1-03 Bersier, M.G. , Miksztowicz, V. , Pe-a , C. , Rodr'guez de Lores Arnaiz, G.
A study of the mechanism of neurotransmitter release enhancement by an endogenous ouabain-like substance

PTW1-04 Zhao, H.W. , Ross, A.P. , Christian, S.L. , Buchholz, J.N. , Drew, K.L.
Suppression of NMDA receptor function in hibernating Arctic ground squirrels

PTW1-05 Miller, T.R., Milicic, I., Wang, J.S., Otte, S., Nikkel, A.L., Bitner, R.S., Drescher, K.U., Fox, G.B., Cowart, M.D., Hancock, A.A., Esbenshade, T.A.
Brain Localization and Neurochemical Effects of the Histamine H3 Receptor Antagonist ABT-239.

PTW1-06 Cheli, V. , Adrover, M. , Blanco, C. , Thomas, J. , Epstein, A. , Jerusalinsky, D.
Identification and quantitation of hippocampal neurons transduced by HSV-1 vectors carrying sense and antisense NR1 transgenes.

PTW1-07 Panizzutti, R. , Rausch, M. , ZurbrŸgg, S. , Baumann, D. , Beckmann, N. , Rudin, M.
The Pharmacological Stimulation of NMDA Receptors Via Coagonist.

PTW1-08 Burdo, J., Dargusch, R., Schubert, D.
The Novel Structure, Distribution and Function of The Brain Cystine Antiporter

PTW1-09 Dai, S.P. , Burkat, P. , Karlsson, M. , Pearce, R.
Exchange Rate Characterization of a Microfluidic Chip and Its Application in Mutation Screen of GABA receptors in HEK293 Cells

PTW1-10 Bhumireddy, P., Arias, H.R.
Characterization of the Antidepressant Binding Site on the Nicotinic Acetylcholine Receptor

PTW1-11 Sutcliffe, J.G., Huitron-Resendiz, S., Henriksen, S.J., Hedlund, P.B.
5-HT7 receptor inhibition and inactivation induce antidepressant-like behavior

PTW1-12 Wallace, D.R., Paulson, J.D.
Nicotinamide-induced alterations in CYP2D6 metabolism of methamphetamine

PTW1-13 Rodr'guez de Lores Arnaiz, G. , Lopez Ordieres, M.G.
The inhibitory effect of neurotensin on neuronal Na+, K+-ATPase activity is altered by clozapine

PTW1-14 Kanjilal, B., Banerjee, P.
Molecular mechanism of the interactions of the atypical antipsychotic drugs with the components of 5HT2A/D2 , 5HT1

PTW1-15 Yao, J.K. , Reddy, R.D. , Keshavan, M.S.
Reduced RBC membrane lipids in first-episode neuroleptic-naove patients with schizophrenia and other psychoses

PTW1-16 Wu, G., Lu, Z., Ledeen, R.W.
The sodium-calcium exchanger complexed with GM1 ganglioside in the nuclear membrane transfers calcium from nucleoplasm to ER


Poster Session PTW-02 Gene Expression and Signalling II

PTW2-01 Sobocki, T. , Jayman, F. , Sobocka, M.B. , Levano, K. , Sridhar, P. , Banerjee, P.
Expression and Functional Role of Mouse ATPase II and ATPase Ib

PTW2-02 Sobol, C.V., Belostotskaya, G.B.
Ca2+ signal in rat brain neurons upon application of probiotic product.

PTW2-03 Heacock, A.M., Fisher, S.K.
Multiple Receptor Regulation of Osmolyte Release from SH-SY5Y Neuroblastoma Cells

PTW2-04 Rodr'guez de Lores Arnaiz, G. , Pereyra-Alfonso , S. , Armanino, M.V. , Pe-a, C. , V‡zquez, C. , Williams, L.
Neurotensin receptor (NTS1) is involved in phosphoinositide hydrolysis enhancement by Na/K ATPase inhibition

PTW2-05 Pannu, R. , Singh, A.K. , Singh, I.
A novel role of lactosylceramide in the regulation of TNF alpha-mediated proliferation of rat primary astrocytes.

PTW2-06 Watters, J.J. , Brautigam, V.M. , Frasier, C. , Nikodemova, M.
PURINERGIC INHIBITION OF NO PRODUCTION IN BV-2 MICROGLIA: POTENTIAL ROLE FOR p38 MAPK/CREB PATHWAY

PTW2-07 Larocca, J., Ortiz, E., Demoliner, K., Si, Q., Rodriguez, A.
Vesicle transport in oligodendrocytes: Role of rRab22b and OCRL-1.

PTW2-08 Bracchi-Ricard, V. , Hu, W. , Mo, X., Brambilla, R. , Li, F. , Walters, M.W. , Blits, B. , He, L. , Schaal, S.M. , Bethea, J.R.
NIBP: A Novel NIK and IKKb binding protein that enhances NF-κB activation

PTW2-09 Bittencourt-Navarrete, R.E., Krahe, T.E., Ramoa, A.S.
Downregulation of ERK during recovery from the effects of a brief period of monocular deprivation (MD)

PTW2-10 Fitzgerald, J.K. , DeVries, G.H.
Signal Transduction in Schwann Cells Stimulated by Axolemma Enriched Fraction


Poster Session PTW-03 Glia and Inflammation II

PTW3-01 Mirochnic, S., Evrard, S.G., Duhalde Vega, M., Tagliaferro, P., Caltana, L., Brusco, A.
Neuronal and astroglial response to a long abstinence period after a chronic ethanol exposure.

PTW3-02 Sun, Y. , Wen, F. , Yao, H.Y.
The Role Of Proinflammatory Cytokines In the Pathogenesis Of Cerebral Palsy

PTW3-03 Reed, J.L. , Wang, C. , Dimayuga, F.O. , Angers, R. , Keller, J.N. , Bruce-Keller, A.J.
The Immunoproteasome in Inflammatory Signaling

PTW3-04 Usuki, S. , Taguchi, K. , Thompson, S.A. , Rivner, M.H. , Yu, R.K.
Sensitization of rats by lipopolysaccharides of Campylobacter jejuni

PTW3-05 Alexander, J.J. , Vezina, P. , Norenberg, M.D. , Quigg, R.J.
Cyclophosphamide and prednisolone in lupus cerebritis - an old therapy revisited

PTW3-06 Parhizgar, S.S., Syapin, P.J.
Effect of Indomethacin on Inducible Proteins in Rat C6 and mouse N9 Glial Cells.

PTW3-07 Jana, M., Dasgupta, S., Dudley, T.M., Liu, X., Pahan, K.
Biological functions of IL-12 p40 homodimer and monomer are different from that of IL-12 p70 and IL-23

PTW3-08 Hamby, M.E., Hewett , J.A., Hewett , S.J.
Astrocytic Nitric Oxide Synthase-2 Expression is Potentiated by Transforming Growth Factor-β1

PTW3-09 Dimayuga, F.O. , Wang, C. , Reed, J.L. , Bauman, G.P. , Strange, J.C. , Bruce-Keller, A.J.
Estrogen Modulates Microglial Respiratory Burst and Expression of Activation Signals for Costimulation and Apoptosis

PTW3-10 Brown III, J.C., Belmadani, A., Kumar, S., Neafsey, E.J., Collins, M.A.
neuroinflammatory-like mechanisms in alcohol-induced brain damage

PTW3-11 Konat, G.W., Banaszewska, M., Krasowska , A.
Double stranded RNA triggers nitric oxide generation and cytokine expression in astrocytes


Poster Session PTW-04 Axon Growth and cytoskeleton

PTW4-01 You, Y. , Morfini, G. , Pigino, G. , Pollema, S. , Marangoni, M.N. , Szebenyi, G. , Brady, S.
Polyglutamine-expanded Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport Through Activation of SAPKs

PTW4-02 Grider, M.H., Shine, H.D.
Expression of Constitutively Active Akt Regulates Morphology of Sensory Neurons

PTW4-03 Seifert, J.L., Hynds, D.L.
ACTIVATION OF RHO GTPases IN NEURONAL GROWTH CONES IN RESPONSE TO EXCITATORY AND INHIBITORY EXTRACELLULAR CUES

PTW4-04 Gallo, G.,
Axonal transport of actin in non-filamentous form

PTW4-05 Lee, J.A., Lau, A., Ku, L., Feng, Y.
FRMP Regulates MAP1B-based Cytoskeletal Dynamics in Growth Cone Development

PTW4-06 Funchal, C., Santos, A.Q., Jacques-Silva, M.C., Zamoner, A., Gottfried, C., Wajner, M., Pessoa-Pureur, R.
Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on GFAP phosphorylation and reorganization

PTW4-07 Sobol, C.V., Belostotskaya , G.B.
Neurons activation and PC-12 differentiation upon application of probiotic product

PTW4-08 Huang, D., Brady, S.T., Gould, R.M.
Kinesin light chain isoforms in rat and spiny dogfish


Poster Session PTW-05 Ischemia

PTW5-01 Dore-Duffy, P., Wang, X.
The role of TWEAK in the CNS microvascular pericyte response to hypoxia

PTW5-02 Kaminska, B., Zawadzka, M., Sliwa, M., Szadujkis, B.
Neuroprotective immunosuppressant FK506 inhibits activation of microglia by interference with signalling pathways

PTW5-03 Sundaresan, R., Satriotomo, I., Bowen, K., Vemuganti, R.
Prevention of transient middle cerebral artery occlusion-induced inflammation and infarction by PPAR-γ agonist treatment in SHR ra

PTW5-04 Cho, S., Liu, D., Wood, A., Reinhart, P., Pangalos, M., Bingham, B.
Ischemia-induced neurogenesis is mediated by increases in stem cell proliferation, migration, and neuronal differentiation

PTW5-05 Yan, Y.P. , Sailor, C.A. , Vemuganti, R. , Dhodda, V. , Dempsey, R.J.
Insulin-Like Growth Factor-1 Is an Endogenous Mediator of Focal Cerebral Ischemia-Induced Neural Progenitor Proliferation

PTW5-06 Satriotomo, I., Bowen, K., Kalluri, H., Vemuganti, R.
Activation of JAK-STAT signal transduction following focal cerebral ischemia

PTW5-07 Luo, J. , Chen, H. , Kintner, D.B. , Shull, G.E. , Sun, D.
Decreased Neuronal Death in Na+/H+ Exchanger Isoform 1 null Mice Following in vitro and in vivo Ischemia

PTW5-08 McKenna, M.C., Lindauer, S.L., Bamford, P., Hopkins, I.B.
H-NMR studies of metabolic alterations in 10-day-old hypoxic/ischemic rat brain

PTW5-09 Alano, C.C. , Ying, W. , Swanson, R.A.
Tricarboxylic acid substrates prevent mitochondrial failure in PARP1 cytotoxicity

PTW5-10 SONG, C.W., KIM, J.G., YEOM, Y.N., HWANG, M.S., KIM, J.H., KOH, S.H., KIM, Y.S., KIM, O.H., JANG, D.D., KIM, S.H.
The change of focal ischemic injured effect after permethrin treated rats

PTW5-11 Zheng, Z. , Qiao, Y. , Dunphy, N. , Ma, J. , Lee, J.E. , Yenari, M.A.
Overexpression of HSP70 inhibits ischemia-induced inflammation in experimental stroke

PTW5-12 Gill, M.B., Hu, X., Perez-Polo, J.R.
Mitochondrial and ER upregulation of Bax in Hypoxia-Ischemia treated P7 Wistar rat pups

PTW5-13 Tang, X.N. , Qiao, Y. , Xu, L. , Giffard, R. , Yenari, M.A.
Microglia enhance blood-brain barrier disruption

PTW5-14 Ling, C., Suresh, M., Sandor, M., Fabry, Z.
CD8 T cells prefer to localize to their antigen-containing site but migrate to traumatic injuries in the CNS

PTW5-15 Yi, J. , Herrero, R. , Danbolt, N.C. , Hazell, A.S.
Upregulation of the EAAT4 glutamate transporter in rat forebrain after traumatic brain


Poster Session PTW-06 Parkinson's and Other Diseases

PTW6-01 Rea Fureigh, K.L. , Nauman, E.A. , Lewus, K.E.
Development and Characterization of a Three-Dimensional Model of the Substantia Nigra for Use in the Study of Parkinson's Disease

PTW6-02 Vatassery, G.T. , Smith, W.E. , Quach, H.T.
Modulation of the effects of L-dopa on PC12 cells by vitamins C and E

PTW6-03 Barcel-Coblijn, G. , Castagnet, P.I. , Golovko, M. , Nussbaum, R.L. , Murphy, E.J.
CHANGES IN LIPID COMPOSITION IN a-SYNUCLEIN GENE-ABLATED MICE ASTROCYTES

PTW6-04 Malecki, E.A. , Reich, S.G. , Moliterno, A.R. , Corse, A.M. , Lee, L.A. , Vogelsang, G.B.
Manganese-Induced Parkinsonism from Total Parenteral Nutrition: Report of a Case and Review of the Literature.

PTW6-05 Hazell, A.S. , Gros, P. , Normandin, L. , Yi, J.H.
Focal accumulation of manganese is correlated with levels of the divalent metal transporter-1 in manganese neurotoxicity

PTW6-06 Huang, Y.L., Huang, Y.L.
Neuronal Nitric Oxide Synthase In Epileptic Fowl

PTW6-07 Schengrund, C.L. , Rosa Borges, A.O. , Puri, A. , Blumenthal, R. , Krebs, F.C. , Johnson, B.T. , Rawat, S.S.
Glycosphingolipids - Portals for Infection

PTW6-08 Yao, H.Y. , Wen, F. , Sun, Y.
Erythropoietin and the Pathogenesis Of Cerebral Palsy

PTW6-09 Wen, F. , Zeng, F. , Yu, S.Z. , Wan, J.C.
Study on nitric oxide and cytology in cerebrospinal fluid from patients with neurocysticercosis

PTW6-10 Dwivedi, Y.,
Neurotrophins in Postmortem Brain of Suicide Vicitms

PTW6-11 Li, W., Esposito, D., Burgess, D., Barnes, A., Creighton, J., Sacktor, N., McArthur, J., Nath, A.
Increased 3-nitrotyrosine modification of proteins in CSF of HIV patients with active dementia and IV drug abusers

PTW6-12 Calkins, M. , Jakel, R.J. , Johnson, D.A. , Johnson, J.A.
Protection from mitochondrial complex II inhibitors by Nrf2-mediated transcription

PTW6-13 Schweitzer, E.S. , Wu, J. , Aiken, C.T.
Lithium prevents enhanced transmitter release and cell death caused by expanded repeat huntingtin

PTW6-14 Kraft, A.D. , Lee, J.M. , Johnson, J.A.
Nrf2 KO mice display a perturbed neural cell damage response which sensitizes them, increasing kainate excitotoxicity severity

PTW6-15 Moser, H.W. , Cox, C. , Dubey, P. , Raymond, G.V. , Loes, D.J. , Moser, A.B.
Cognitive Function in Asymptomatic X-Linked Adrenoleukodystrophy Patients

PTW6-16 Chen, J. , Wen, F. , Wang, Q.
Study of quantitative detection Mycobacterium tuberculosis in cerebrospinal fluid using TaqMan-PCR technique

PTW6-17 Chen, J. , Wen, F. , Wang, Q.
PCR-molecular beacon assay for detecting Mycobacterium tuberculosis in cerebrospinal fluid


Poster Session PTW-07 Demyelination

PTW7-01 Gavrilyuk, V., Sharp, A., Lin, S., Polak, P., Feinstein , D.L.
Astrocytic PPARg is not necessary for protective effects in EAE

PTW7-02 Nelson, J. , Kinra, T.D. , Becker-Catania, S. , Feinstein, D. , DeVries, G.H. , Kennett, R.H.
Anti-axolemma antibodies in experimental allergic encephalomyelitis and multiple sclerosis

PTW7-03 Lalive, P.H., Menge, T., Hauser, S.L., Genain, C.G.
Serum Neuronal Toxicity in Multiple Sclerosis

PTW7-04 Lalive, P.H., Menge, T., Hauser, S.L., Genain, C.P.
Serum IgG reactivity against MOG-transfected cells is selectively increased in specific clinical subtypes of multiple sclerosis

PTW7-05 Dutta, R., Torres, T., McDonough , J., Trapp, B.D.
CNTF induces an Anti-apoptotic response in non-lesion motor cortex of MS patients

PTW7-06 Wang,, Q. , Wen, F.
A study of nitric oxide in cerebrospinal fluid of patients with inflammatory demyelinating disease

PTW7-07 Wilkins, A. , Compston, A. , Duncan, I.
Axonal degeneration in the taiep rat

PTW7-08 Crocker, S.J. , Lin, W. , Frausto, R.F. , Popko, B. , Whitton, J.L. , Campbell, I.L.
Demyelination Induced by EAE or Cuprizone Evoke Distinct Patterns of MMP and TIMP Expression in the Central Nervous System

PTW7-09 Pfeiffer, S.E. , Marta, C.B. , Oliver, A.R. , Sweet , R.A. , Ruddle, N.H.
Encephalitogenic and non-encephalitogenic anti-MOG: Differences in determinant recognition and effects on OL physiology

PTW7-10 Campagnoni, A.T. , Jacobs, E.C. , Pribyl, T.M. , Kampf, K. , Campagnoni, C.W. , Colwell, C.S. , Reyes, S.D. , Martin, M., Handley, V.W. , Hiltner, T.D. , Readhea
Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene

PTW7-11 Kondo, Y., Duncan, I.D.
Exogenous enzyme replacement rescues mutant oligodendrocytes of the twitcher mouse and promotes their stable myelination in vivo

PTW7-12 Pasquini, L.A., Calatayud , C.A., Soto, E.F., Pasquini, J.M.
Cuprizone neurotoxicity on oligodendrocytes requires TNF alpha and IFN gamma

PTW7-13 Shukla, D.K. , Kaiser, C. , Stebbins, G.T. , Thulborn, K.R. , Feinstein, D.L.
Multi-modal imaging of Relapsing MS patients

PTW7-14 Benjamins, J.A., Nedelkoska, L.
Metabotropic Glutamate Receptors 1 and 5 Activate Protein Kinase G to Protect Against Kainate Excitotoxicity in Oligodendrocytes

PTW7-15 Connor, J.R. , Zhang, X. , Haaf, M. , Grosstephan, E. , Surguladze, N. , Todoric, B.
Cytokine Toxicity To Oligodendrocytes Is Mediated By Iron


Poster Session PTW-08 Remyelination and Differentiation

PTW8-01 Mao, J. , Polak, P. , Sharp, A. , Wu, C. , Wei, J. , Gould, R.M. , Wang, Y. , Feinstein, D.L.
Toward In Vivo Detection of Remyelination

PTW8-02 Chen, Y., Feng, Y.
QuakingI promotes oligodendrocyte differentiation after cell cycle exit

PTW8-03 Gadea, A., Haydar, T., Aguirre, A., Gallo, V.
A novel role for endothelin 1 as a regulator of oligodendrocyte development

PTW8-04 Paez, P.M., Garcia, C.I., Soto, E.F., Pasquini, J.M.
Apotransferrin modulates MBP expression through different transcription factors in two oligodendroglial cell lines

PTW8-05 Bansal, R. , Marin-Husstege, M. , Bryant, M. , Casaccia-Bonnefil, P.
S-phase entry of oligodendrocyte lineage cells is associated with increased levels of p21Cip1

PTW8-06 Filipovic, R., Zecevic , N.
Development of oligodendrocyte lineage in the human fetal brain is promoted by chemokine GRO-alpha: a possible mechanism

PTW8-07 Molloy, G.R., Shen, W.
Expression of brain creatine kinase increases in primary oligodendrocytes during in vitro differentiation.

PTW8-08 HAO, Q., Fujita, Y., Macklin, W.B.
Differentiation of proteolipid protein-expressing cells in the developing telencephalon.

PTW8-09 Nielsen, J.A. , Maric, D. , Lau, P. , Barker, J.L. , Hudson, L.D.
Analysis of Gene Expression During the Early Stages of Oligodendrocyte Differentiation

PTW8-10 Frederick, T.J., Mitchell, N.E., Altieri, S., Wood, T.L.
Synergistic induction of cyclin D1 in OP cells by IGF-I and FGF-2 requires differential stimulation of two signaling pathways

PTW8-11 Salis, C., Urtasun, N., Soto , E.F., Pasquini, J.M., Setton-Avruj, C.P.
Schwann cells differentiation is affected by the redox state

PTW8-12 Priyadarshini, S., Flores, A.I., Macklin, W.B.
Neuregulin regulates myelination through Akt signaling in oligodendrocytes

PTW8-13 Becker-Catania, S.G. , Nelson, J.K. , De Vries, G.H.
Axonal Plasma Membrane Factors Modulate Oligodendrocyte Progenitor Activity



Oral Sessions O1-O4 (Sunday, Monday, Wednesday)

Oral Session O1 (Sunday) Neurotoxicology
Chairs: R. Wiggins and N. Banik
O1.1 Bennett, K.
Estrogen treatment and immunoselection of basal forebrain cholinergic neurons
O1.2 Adibhatla, R.M.
Cytokines, Lipid Metabolism, and CDP-choline in Stroke
O1.3 Rama Rao, K.V.
Manganese-induced astrocyte swelling: role for the low grade brain edema in chronic hepatic encephalopathy
O1.4 Jeitner, T.M.
Hydrogen sulfide as a scavenger of HOCl
O1.5 Madrigal, J.M.
Neuroprotection by noradrenaline; Effects on neuronal IkB-alpha and PPAR receptors
O1.6 Mongin, A.A.
Comparison of Pharmacological Profiles of Volume-Regulated Cl- Currents and Excitatory Amino Acid Release in Cultured Astrocytes
O1.7 Samantaray, S.
Presence of MPP<sup>+</sup> and motoneuron apoptosis with calpain activation in spinal cord of mice with MPTP-induced parkinsonism


Oral Session O2 (Monday) Oligodendrocytes: Life, Death, and Resurrection
Chairs: M. Gardinier and P. Wight
O2.1 Lang, J.K.
BMP Regulation of Adult Human Oligodendrocyte Progenitor Fate
O2.2 McLaughlin, M.
Dynamics and cellular transport of PLP is altered in the rumpshaker mutant
O2.3 Shankar, S.L.
Gas6/Axl signaling protects oligodendrocytes from TNF-induced apoptosis via the PI3 kinase/Akt survival pathway
O2.4 Skundric, D.S.
Neutralization of IL-16 reduces inflammation, demyelination, axonal damage, and reverses paralysis during relapsing-remitting EAE
O2.5 Grinspan, J.B.
Induction of bone morphogenetic proteins in mouse spinal cord during experimental autoimmune encephalomyelitis
O2.6 Fressinaud, C.
NT-3 and PDGF partially restore mature oligodendrocyte plasticity after multiple insults in vitro
O2.7 Gao, L.M.
Specification of optic nerve oligodendrocyte precursors by retinal ganglion cell axons.


Oral Session O3 (Wednesday) Glia and Neurological Disorders
Chairs: R. Swanson and M. Brenner
O3.1 Westmark, C.
FMRP Mediates mGluR1-Activated Translation of Amyloid Precursor Protein
O3.2 Dello Russo, C.
A new HSP90 inhibitor reduces experimental autoimmune encephalomyelitis
O3.3 Li, J.
Nrf2-dependent ARE activation is a gain of function alteration specific to differentiated astrocytes.
O3.4 Jana, A.
HIV-1 neurotoxic proteins and activated astroglia kill human primary neurons via neutral sphingomyelinase
O3.5 Carpentier, P.A
The role of protein kinase R in the activation of astrocytes by viral infection
O3.6 Yamada, M.
BMP signaling regulates glial scarring
O3.7 Brambilla, R
Inhibition of astroglial NF-kB reduces inflammation and improves functional recovery following spinal cord injury


Oral Session O4 (Wednesday) Intracellular signaling in Glia and Neurons
Chairs: A. Gow and B. Fuss
O4.1 Saha, R.N.
Greater availability of NF-kB p65:p50 in glia than neurons: Implications for neurodegenerative disorders
O4.2 Lin, W.
ER Stress Modulates the Response of Myelinating Oligodendrocytes to the Immune Cytokine Interferon-gamma
O4.3 Marta, C.B.
Elucidating the Mechanism of anti-MOG Antibody-Mediated Demyelination
O4.4 Zhang, Z.
Activation of the Caspase Independent Pathway in PLP Overexpresser Mice
O4.5 Morfini, G.
Molecular Mechanisms Underlying Kinesin Inhibition by Polyglutamine-expanded proteins.
O4.6 Hynds, D.L.
Inhibition of RhoA Signaling Decreases Actin Filament Content in Neuroblastoma Growth Cones