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Saturday, 3/19 | Sunday, 3/20 | Monday, 3/21 | Tuesday, 3/22 | Wednesday, 3/23 |
= Meeting
= Ticketed Event with Lunch
=Ticketed Event
SATURDAY, MARCH 19 |
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9:00 am - 6:00 pm | ![]() |
9:00 am - 12:00 pm Sponsored by |
Chair: David Baker, PhD
PMW1.01 – Circuit-Specific Synaptic Regulation by Astrocytes Alfonso Araque, PhD - University of Minnesota
Darwin Berg, PhD - University of California, San Diego
PMW1.03 - Control Your Excitement: Astrocyte Regulation of Glutamate Signaling in the Developing and Injured Brain |
12:00 pm - 5:00 pm |
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1:00 pm - 3:00 pm Sponsored by
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![]() FROM SINGLE CELL TRANSCRIPTOMES TO FUNCTIONAL CIRCUITS: NEW FINDINGS FROM THE ALLEN INSTITUTE FOR BRAIN SCIENCE FRONTLINE
$No Charge More details Chair: Jane Roskams, PhD PMW02-01 - Mapping Cortical Areas in GCaMP6 Reporter Mice with Widefield Imaging |
3:00 pm - 3:30 pm |
Coffee Break |
3:30 pm - 6:30 pm Sponsored by |
Chair: Jane Roskams, PhD Speaker: Terri Gilbert, PhD |
4:00 pm - 5:30 pm |
ASN Public Forum on MS Mt. Sopris
Chair: Wendy Macklin, MD, PhD Timothy Vollmer, MD - University of Colorado |
6:00 pm - 7:30 pm Sponsored by |
ASN President's Welcome Reception Capital Peak, 38th floor |
SUNDAY, MARCH 20 |
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7:00 am - 6:00 pm |
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8:15 am - 8:30 am |
President’s Welcome & Introductions Aspen Ballroom |
8:30 am - 9:30 am |
Presidential Lecture 01: Aspen Ballroom |
9:30 am - 10:00 am |
Coffee Break: View Posters & Visit Exhibits |
10:00 am - 12:00 pm |
Plenary Lecture PL01: Aspen Ballroom Chair: Bruce D. Carter, PhD Co-Chair: Carla J. Shatz, PhD PL01-01 - Cortical Interneuron Fate, A Tale of Two Proliferative Zones |
12:15 pm - 1:30 pm |
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12:15 pm - 1:30 pm Sponsored by |
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1:30 pm - 3:30 pm Sponsored by |
S01 - Myelination: Aspen Ballroom Chair: Donna J. Osterhout, PhD Co-Chair: J. Bradley Zuchero, PhD S01-01 - Submembranous Cytoskeleton Stabilizes Specialized Membrane Domains at Nodes of Ranvier Keiichiro Susuki, PhD - Wright State University
S01-02 - How Does the Actin Cytoskeleton Drive Myelin Wrapping? J. Bradley Zuchero, PhD - Stanford University
S01-03 - A Glutamate Transporter-CaMKIIbeta Signaling Axis as a Regulator of Oligodendrocyte Morphogenesis and CNS Myelination Babette Fuss, PhD - Virginia Commonwealth University
S01-04 - Fyn Signaling and the Cytoskeleton in Oligodendroglia |
1:30 pm - 3:30 pm |
S02 - Axon-Glia Interactions in Development and Disease Mt. Sopris
Chair: Tara M. DeSilva, PhD Co-Chair: Marc R. Freeman, PhD S02-01 - Axon-Glia Interaction in Drosophila Marc R. Freeman, PhD – Howard Hughes Medical Institute
S02-02 - Genetic Dissection of Schwann Cells, Oligodendrocytes and Microglia in Zebrafish William Talbot, PhD – Stanford University
S02-03 - Glutamatergic Signaling in Myelination and Demyelination in Rodent Models of Development and Disease Tara M. DeSilva, PhD - University of Alabama, Birmingham
S02-04 - Mechanisms of Neuroglial Damage in Mouse Models of Multiple Sclerosis |
3:30 pm - 4:00 pm |
Coffee Break: View Posters & Visit Exhibits |
4:00 pm - 5:30 pm |
C01 - Keeping Time: Roles of Circadian Genes Aspen Ballroom
Chair: Gregorio Valdez, PhD C01-01 - Clock Plays a Key Role in the Timely Development and Repair of Neuromuscular Synapses Gregorio Valdez, PhD - Virginia Tech
C01-02 - Loss of Clock Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy Judy Liu, MD, PhD - Children's National Health System
C01-03 - Cell Type-Specific Functions of the Circadian Clock in Neuroiflammation and Neurodegeneration Eric Musiek, PhD – Washington University in St. Louis
C01-04 - Secreted Glial Proteins that Regulate Adult Drosophila Behavior |
4:00 pm - 5:30 pm |
C02 - Astrocytes as Excitation-Energy Coupling Hubs Mt. Sopris
Chair: Robert Zorec, PhD Co-Chair: Arne Schousboe, DSc C02-01 - Noradrenaline and Aerobic Glycolysis in Astrocytes Gerald Dienel, PhD - University of Arkansas
C02-02 - Regulation of Glycogen Breakdown in Astrocytes by Distinct Glycogen Phosphorylase Isoforms Helle Waagepetersen, PhD - University of Copenhagen
C02-03 - Lactate Receptor in the Brain Linda H. Bergersen, PhD - University of Copenhagen
C02-04 - Adrenergic Control of Astrocyte Function |
4:00 pm - 5:30 pm |
OR01 - Oral Session I: Presentation of Selected Abstracts Maroon Peak Chair: Michael A. Fox, PhD OP01-01 - OLFACTORY BULB BUT NOT CORTICAL CAPILLARIES ARE SUSCEPTIBLE TO VIRUS-INDUCED VASCULAR LEAK AND PROMOTE VIRAL NEUROINVASION OP01-02 - AN AUTOMATED BEHAVIORAL PARADIGM REVEALS CEREBELLAR DEFICITS IN A MOUSE MODEL OF PREMATURE BIRTH INJURY OP01-03 - DIFFERENTIAL PERIPHERAL AND CENTRAL NERVOUS SYSTEM REGULATION OF SELF-REACTIVE CD4 TCELLS DURING VIRAL ENCEPHALOMYELITIS OP01-04 - CHEMOGENETIC ACTIVATION OF SATELLITE GLIAL GQ-GPCR SIGNALING ENHANCES CARDIAC FUNCTION IN VIVO OP01-05 - BRAIN ENDOTHELIAL CXCL10 MEDIATES LPS-INDUCED MICROGLIAL ACTIVATION AND NEUROPROTECTION IN MICE |
5:30 pm - 7:00 pm |
Poster Session I - Authors Present Colorado Ballroom |
7:30 pm - 10:00 pm |
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MONDAY, MARCH 21 |
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7:00 am - 5:00 pm |
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8:15 am - 8:30 am |
General Session - Opening Remarks Aspen Ballroom
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8:30 am - 9:30 am |
Presidential Lecture 02: Aspen Ballroom |
9:30 am - 10:00 am |
Coffee Break: View Posters & Visit Exhibits |
10:00 am - 12:00 pm
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Plenary Lecture PL02: Aspen Ballroom Chair: Michael A. Fox, PhD Co-Chair: Dorian McGavern, PhD PL02-01 - title tba PL02-04 - Glia Targets for Cognitive Enhancement and the Treatment of Alzheimer's |
12:15 pm - 1:30 pm |
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12:15 pm - 1:30 pm |
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1:30 pm - 3:30 pm |
S03 - Complement in CNS Health and Disease Aspen Ballroom Chair: Robyn S. Klein, MD, PhD S03-01 - Repair from the Perspective of an Inflammatory Niche and the Complement CascadeAileen Anderson, PhD – University of California, Irvine S03-02 - How Complement Eliminates Specific Synapses in Health & Disease Andrea Tenner, PhD – University of California, Irvine S03-04 - A Complement-Microglial Axis is Required for Synapse Elimination During Virus-Induced Memory Impairment |
1:30 pm - 3:30 pm |
S04 - Astrocyte Heterogeneity: From Molecular Mt. Sopris
Chair: Michael B. Robinson, PhD S04-01 - Decoding Molecular and Functional Diversity of Astrocytes in the Normal and Pathological Brain Benjamin Deneen, PhD - Baylor College of Medicine
S04-02 - Astrocyte Molecular and Functional Heterogeneity in Neural Circuit Formation Anna Victoria Molofsky, MD, PhD - University of California, San Francisco
Tobias Stork, PhD - University of Massachusetts
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3:30 pm - 4:00 pm |
Coffee Break: View Posters & Visit Exhibits |
4:00 pm - 5:30 pm |
C03 - Neural Development and Regeneration Mt. Sopris Chair: Wenqin Luo, MD, PhD Co- Chair: Tracy Tran, PhD C03-01 - Floor Plate-Derived Neuropilin 2 Functions as a Secreted Semaphorin Sink to Facilitate Commissural Axon Midline Crossing Tracy S. Tran, PhD - Rutgers University
C03-02 - Midline Radial Glial-Like Cells Promote Ipsilateral Longitudinal Growth of Spinal Cord Dorsal Column Axons During Development Wenqin Luo, MD, PhD - University of Pennsylvania, Perelman School of Medicine
C03-03 - Seeing is Believing: Peripheral Nerve Regeneration in Zebrafish Michael Granato, PhD - University of Pennsylvania, Perelman School of Medicine
C03-04 - AKT Coordinates the Signaling of mTORC1 and mTORC2 To Promote CNS Axon Regeneration Yang Hu, MD, PhD - Lewis Katz School of Medicine at Temple University
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4:00 pm - 5:30 pm |
C04 - Dissecting the Effects of Chronic Stressors Maroon Peak
Chair: Justin Brooks, PhD Co-Chair: Yelena Grinberg, PhD C04-01 - Multiple Drivers of Pathogenesis In CD4 T Cell-Driven Epilepsy Yelena Grinberg, PhD – University of California, Riverside
C04-02 – Role of Exosomes in Promoting CNS Myelination / Remyelination Aya Pusic, PhD - University of Chicago
C04-03 - CNS Effects of Opiate Exposure in a Mouse Model of NeuroAIDS: Selective Vulnerability of D1 And D2-Expressing Medium Spiny Neurons Christina Schier, PhD - Virginia Commonwealth University
C04-04 - Toxoplasma Gondii Infections Alter GABAergic Synapses and Signaling in the CNS Justin Brooks, PhD - State University of New York at Buffalo |
4:00 pm - 5:30 pm |
C05 - Functions of Astrogliosis Aspen Ballroom Chair:Joshua Burda, PhD- Marian Kies awardee C05-01 - Reactive Astrocytes and Synaptic Plasticity Giulia Tyzack, PhD – University of Cambridge
C05-02 - Dissecting Region-Specific Forms of Trauma-Reactive Astrogliosis In Vivo by Cell-Type Specific Analysis of Translating mRNA Joshua Burda, PhD - University of California, Los Angeles
C05-03 – Novel In Vitro Systems to Study Reactive Astrocytes Shane Liddelow, PhD - Stanford University
C05-04 – Glial Engulfment Function in the Developing and Mature Brain Marc Freeman, PhD – University of Massachusetts |
5:30 pm - 6:00 pm |
New and Early Stage Investigators Funding Opportunities Aspen Ballroom |
6:00 pm - 7:30 pm |
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TUESDAY, MARCH 22 |
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7:00 am - 5:00 pm |
ASN Registration Desk Open |
8:15 am - 8:30 am |
General Session - Opening Remarks Aspen Ballroom |
8:30 am - 9:30 am |
Presidential Lecture 03: Aspen Ballroom |
9:30 am - 10:00 am |
Coffee Break: View Posters & Visit Exhibits |
10:00 am - 12:00 pm |
Plenary Session PL03: Aspen Ballroom Chair: Vladimir Parpura, MD, PhD Co-Chair: J. David Sweatt, PhD PL03-01 - Mechanism of Rapid Antidepressant Action |
12:15 pm - 1:30 pm |
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1:30 pm - 3:30 pm |
S05 - Paradoxical Role of Interleukin-1beta in Aspen Ballroom
Chair: James Hewett, PhD S05-01 - Inflammasome Activation and IL-1β Affect Neurodegeneration in Juvenile Batten Disease Tammy L. Kielian, PhD - University of Nebraska
S05-02 - Bimodal Actions of IL-1β in Stroke-Related Models Sandra Hewett, PhD - Syracuse University
S05-03 - Sustained IL-1β Over Expression Reduces Amyloid Plaques via Alternative Microglial Activation M. Kerry O’Banion, PhD - University of Rochester
S05-04 - Endogenous Interleukin-1β Suppresses Acute Epileptic Seizures and Status Epilepticus |
1:30 pm - 3:30 pm |
S06 - Emerging Role of Glia in Neuronal Mt. Sopris
Chair: Wenzhen Duan, MD, PhD - Johns Hopkins S06-01 - Juvenile Striatal White Matter is Resistant to Ischemia-Induced Damage Wendy Macklin, MD, PhD - University of Colorado, Denver
S06-02 - New Tools to Explore Astrocyte Signaling in Neural Circuits Baljit S. Khakh, PhD - University of California, Los Angeles
S06--03 - An NFκB/Complement-Mediated Neuron-Glia Signaling Pathway in Neuronal Health and Alzheimer’s Disease Hui Zheng, PhD - Baylor College of Medicine
S06-04 - Dysmyelination in Huntington’s Disease |
3:30 pm - 4:00 pm |
Coffee Break: View Posters & Visit Exhibits |
4:00 pm - 5:30 pm |
C06 - Dynamics of DNA Damage Responses, Aspen Ballroom
Chair: Muralidhar Hegde, PhD Co-Chair: Sankar Mitra, PhD C06-01 - New Evidence for RNA/DNA Binding Proteins'-Mediated Genome Repair Defects in Motor Neuron Disease Muralidhar Hegde, PhD - Houston Methodist Research Institute
C06-02 - DNA Repair Gone Wrong: Mechanisms of Trinucleotide Expansion in Human Neurodegenerative Disease Cynthia McMurray, PhD - Lawrence Berkeley National Laboratory
C06-03 - Studies on Synuclein Induced DNA Conformation/Damage in Relevance to Parkinson Disease Jagannatha Rao, PhD - Institute for Scientific Research and Technology Services
C06-04 -Nuclear to Mitochondrial DNA Damage Signaling in Neurodegeneration Vilhelm Bohr, MD, PhD - Gerontology Research Center of the National Institutes of Health
C06-05 - Oxidative Genome Damage and Its Response in Proliferating vs. Postmitotic Cells: Implications in Neurodegenerative Diseases |
4:00 pm - 5:30 pm |
C07 - Glia-Neuron Interactions in CNS Injury Mt. Sopris
Chair: Shinghua Ding, PhD Co-Chair: Long-Jun Wu, PhD C07-01 - Microglia-Neuron Communication in Epilepsy Long-Jun Wu, PhD - Rutgers University
C07-02 - Mechanisms of Spreading Depolarization-Induced Cytotoxic Edema Sergei Kirov, PhD - Georgia Regents University
C07-03 - The Immune Response to CNS Injury is Orchestrated by Oligodendrocyte-Derived IL-33 Sachin Gadani - University of Virginia
C07-04 - Microglia, Neurogenesis and Stroke Stella E. Tsirka, PhD - Stony Brook University
C07-05 - Role of Astrocytic GDNF in Neurogenesis and Brain Damage after Ischemic Stroke |
4:00 pm - 5:30 pm |
OR02 - Oral Session II: Presentation of Selected Abstracts Maroon Peak
Chair: Gregorio Valdez, PhD OP02-01 - MICROGLIAL LIPOPROTEIN RECEPTOR LRP1 REGULATES NEURO-INFLAMMATION: APPLICATIONS FOR MULTIPLE SCLEROSIS OP02-02 - GPR126/ADGRG6 HAS SCHWANN CELL AUTONOMOUS AND NON-AUTONOMOUS FUNCTIONS IN PERIPHERAL NERVE INJURY AND REPAIR OP02-03 - A PIVOTAL ROLE OF TESTOSTERONE AND THE ANDROGEN RECEPTOR IN MYELIN REGENERATION OP02-04 - NOVEL ROLES FOR SPON1 IN ESTABLISHING CIRCUITS AND BEHAVIORS ASSOCIATED WITH CIRCADIAN PHOTOENTRAINMENT OP02-05 - MYELIN REMODELING AND EXPERIENCE-DEPENDENT OLIGODENDROGENESIS PERSIST IN THE MIDDLE-AGED BRAIN |
5:30 pm - 7:00 pm |
Poster Session II - Authors Present Colorado Ballroom
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7:00 pm - 9:00 pm |
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WEDNESDAY, MARCH 23 |
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7:00 am - 5:00 pm | ![]() |
8:15 am - 8:30 am |
General Session - Opening Remarks Aspen Ballroom |
8:30 am - 9:30 am Sponsored by |
Presidential Lecture 04: Aspen Ballroom
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9:30 am - 10:00 am |
Coffee Break: View Posters & Visit Exhibits |
10:00 am - 12:00 pm Sponsored by |
Plenary Lecture PL04: Aspen Ballroom Chair: Bruce Appel, PhD Co-Chair: Linda B. Buck, PhD PL04-01 - Identification, Validation and Targeting of Human Molecular Networks Contributing to Neurodegeneration and Cognitive Decline |
12:00 pm - 3:30 pm |
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12:15 pm - 1:30 pm |
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1:30 pm - 3:30 pm Sponsored by
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S07 - Enhancing Remyelination During Multiple Sclerosis Aspen Ballroom Chair: Alban Gaultier, PhD Co-Chair: Benjamin Deneen, PhD S07-01 - Glial Interactions Modulating Demyelination and Remyelination Robert Miller, PhD - George Washington University
S07-02 - Developmental Gliogenesis: New Perspectives and Paradigms for Repairing the CNS Hyun-Kyoung Lee, PhD - Baylor College of Medicine S07-03 - LRP1 Function During Remyelination Alban Gaultier, PhD - University of Virginia S07-04 - In Vitro Generated Oligodendrocyte Progenitor Cells Provide a Platform for Discovery of Remyelinating Therapeutics |
S08 - Mechanisms of Mutant C9ORF72 Pathogenesis Mt. Sopris
Chair: Rita G. Sattler, MS, PhD Co-Chair:Tania Gendron, PhD S08-01 - Synaptic Dysfunction in C9ORF72 ALS and FTD Rita G. Sattler, MS, PhD - Barrow Neurological Institute
S08-02 - Dipeptide Repeat Proteins in C9ORF72 Frontotemporal Dementia and Amyotrophic Lateral Sclerosis Tania Gendron, PhD - Mayo Clinic
S08-03 - Nucleocytoplasmic Trafficking Deficits Underlie C9ORF72ALS/FTD Neural Injury Christopher Donnelly, PhD - University of Pittsburgh
S08-04 -Insights from Drosophila and iPSC Models of C9ORF72 Repeat Expansion
S08-05 -Mechanisms of Neurotoxicity Mediated by C9ORF72-linked Dipeptide Repeat Proteins |
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3:30 pm - 4:00 pm |
Coffee Break: Visit Exhibits |
4:00 pm - 5:30 pm Sponsored by |
C08 - Non-Traditional Approaches to Study Glial Cell Biology Mt. Sopris Chair: Kelly Monk, PhD Co-Chair: Sarah Kucenas, PhD C08-01 - Genetic Screens in Zebrafish Uncover New Regulators of Myelinating Glial Cell Development Kelly Monk, PhD – Washington University of St. Louis
C08-02 - Glia Establish Structural and Functional Set Points in the Nervous System Shai Shaham, PhD - Rockefeller University
C08-03 - Transcriptional Profiling of Drosophila Glia Responding to Injury Mary Logan, PhD - Oregon Health and Science University
C08-04 - Engineering Pseudo-Axonal Scaffolds for Myelination: Implications for Development, Disease and High Throughput Screening Jonah Chan, PhD - University of California, San Francisco
C08-05 - Peering Through the Looking Glass: The Role of Glial-Glial Interactions Across Transition Zones in Development and Disease |
C09 - Unmyelinated and Unappreciated: Novel Roles of Aspen Ballroom
Chair: Marion S. Buckwalter, MD, PhD Co-Chair: Brian D. Gulbransen, PhD C09-01 - Development and Function of Drosophila Wrapping Glia Megan Corty, PhD - University of Massachusetts Medical School
C09-02 - Regulation of Enteric Neural Networks by Enteric Glia in Health and Disease Brian Gulbransen, PhD - Michigan State University
C09-03 - Enteric Glia Protect the Mucosal Barrier Tor Savidge, PhD - Baylor College of Medicine
C09-04 - Understanding and Targeting Dysfunctions of the Digestive Neuro-Glio- Epithelial Unit in Digestive and Brain Disorders Michel Neunlist, PhD - Université de Nantes, Inserm
C09-05 - Pulmonary Glia |
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C10 - Old Friends and New Roles: Brain Patterning Maroon Peak
Chair: Anthony P. Barnes, PhD C10-01 - Functions of ERK/MAP Kinase Signaling in Developing Cortical Circuits Jason Newbern, PhD - Arizona State University
C10-02 - JNK Signaling: A Molecular Compass for Migratory Cortical Interneurons Eric S. Tucker, PhD - West Virginia University
C10-03 - New Insight into NCL-Associated Proteins: Novel Regulators of Cargo Transport in Neurons Jill M. Weimer, PhD - Children’s Health Research Center at Sanford Research
C10-04 - Endolysosomal Trafficking and Signaling During Brain Development |
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7:30 pm - 11:00 pm Sponsored by
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ASN Closing Reception / Dinner / Dancing Capital Peak, 38th floor |